How does Black seed benefit?
The mechanism by which Black seed exerts its antiinflammatory action appears to be as a potent inhibitor of thromboxane B 2 and leucotrienes B 4, by inhibiting both cyclooxygenase and lipooxygenase, respectively.
In the United States, 150,000 patients are hospitalized because of asthma, and around 5 million patients have the disease. Bronchial asthma is a genetically based, multifactorial disease that is aggravated by a number of factors such as infections, allergen exposure, tobacco smoke and environmental pollutants.
Stabilization of the arachidonic acid metabolism via modulation of prostaglandin and leukotriene production, and stabilization of interleukins and tumor necrosis factor (TNF) has been shown to safeguard the body from allergic reactions.
Four Human studies showed that black seed oil is indeed capable of relieving symptoms of allergic rhinitis, atopic eczema, and bronchial asthma.
Very recently, researchers at Kimmel Cancer at Jefferson in Philadelphia discovered that thymoquinone blocked pancreatic cancer cell growth and killed the cells by enhancing the process of programmed cell death.
black seed oil could be effectively used to treat hypertension. In fact, the authors suggested that the diuretic action of black seed might be, at least partially, responsible for its antihypertensive action related to its volatile oils.
Diabetes mellitus results in severe metabolic imbalances and pathological changes in many tissues. Oxidative stress has been shown to play an important role in the etiology of diabetes and diabetic complications.
Black seed increases the numbers of sperm and helps with fertility and performance for men and women with no side affects. (Helps preserve marriage and families!) Courtesy of www.blessedsunnah.com
Several studies point to the effect of black seed and thymoquinone on the immune system by modulating the levels of pro- and anti-inflammatory mediators. Thymoquinone has also been shown to inhibit inflammation and oxidative stress in cells. The seeds have been shown to produce an increase in the ratio of helper to suppressor T cells and enhance natural killer cell activity in healthy volunteers.
Black seed oil has been shown to possess antiparasitic properties comparable to those of some of the leading pharmaceuticals. In one study, black seed oil was effective in reducing the number of Schistosoma mansoni worms in the liver and decreased the total number of ova deposited in both the liver and the intestine. Furthermore, it increased the number of dead ova in the intestinal wall and markedly reduced the granuloma diameters. Administration of black seed oil concomitantly with the leading flatworm pharmaceutical, lowered further the number of dead ova than was observed when the drug was given alone, indicating that the plant oil potentiates the action of the drug.
Nearly 15% of childhood epilepsy cases are resistant to treatment. Many of the drugs used to treat epilepsy produce unwanted side effects or are capable of producing serious adverse events. When epilepsy remains uncontrolled, it is termed refractory or pharmacoresistant. A recent study found black seed oil has anticonvulsant effects and improved seizure control in children suffering from refractory epilepsy. Earlier animal studies have also demonstrated the anticonvulsant effects of thymoquinone. Researchers hypothesized that thymoquinone may have anticonvulsant activity in petit mal epilepsy probably through an opioid receptor-mediated increase in GABAergic tone. They have also suggested black seed's potent antioxidant properties may be responsible for preventing seizures as well.
Likewise, thymoquinone protected against the ulcerating effect of alcohol and mitigated most of the biochemical adverse effects induced by alcohol in gastric mucosa, but to a lesser extent than whole black seed. Researchers also hypothesized that thymoquinone's antihistaminic effect could play a role in preventing gastric injury as an antihistaminic effect has been shown to be an important preventive mechanism against gastric injury.
Ibn Sina (980-1037), in describing the black seed as that which "stimulates the body's energy and helps recovery from fatigue or disspiritedness," still holds true for Tibb (Islamic Medicine) health practitioners today. The rich nutritional value contained in black seed as outlined by scientific research.